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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2094844Generated: October 30, 2026

Pyrimidin-5-ylmethanamine → HCID 178518108, compound

https://huagongshe.com/reaction/2094844

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyrimidin-5-ylmethanamineHCID 18953632—
Reactant5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-methylsulfanyl-thiazolidin-4-oneHCID 86656522—
ProductHCID 178518108HCID 178518108—

Reaction Steps

5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-[(pyrimidin-5-ylmethyl)-amino]-thiazol-4-one was prepared from 5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-methylsulfanyl-thiazolidin-4-one and C-Pyrimidin-5-yl-methylamine following General Procedure B.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08445690B2
Source datasetuspto-grants-2013_05
ORD IDord-b81bed74c0b84f72833f8d1d413f850b
Source noteuspto-grants-2013_05