Phenethylamine → HCID 57422339, compound

HRID 2094898Notes

Reaction equation

HRID 2094898 reaction equation
[C:1]1([CH2:7][CH2:8][NH2:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.Cl[S:11]([C:14]1[CH:23]=[CH:22][C:17]([C:18]([O:20]C)=[O:19])=[CH:16][CH:15]=1)(=[O:13])=[O:12].Cl[CH2:25][C:26]1[CH:31]=[CH:30][C:29]([O:32][CH3:33])=[CH:28][CH:27]=1>>[CH3:33][O:32][C:29]1[CH:30]=[CH:31][C:26]([CH2:25][N:9]([CH2:8][CH2:7][C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)[S:11]([C:14]2[CH:23]=[CH:22][C:17]([C:18]([OH:20])=[O:19])=[CH:16][CH:15]=2)(=[O:13])=[O:12])=[CH:27][CH:28]=1

Participants

4

Reactant 3

HCID 1001PhenethylamineHCID 699934-Methyloxybenzyl chlorideHCID 4738388Methyl 4-(Chlorosulfonyl)benzoate

Product 1

HCID 57422339HCID 57422339, compound

Procedure

Prepared as in example 5-10 from 2-phenylethanamine, methyl 4-(chlorosulfonyl)-benzoate (Example 5-10c) and 1-(chloromethyl)-4-methoxybenzene. MS (M−H, 424.1); 1H NMR (400 MHz, DMSO-d6): δ, ppm: 2.51 (m, 2H), 3.23 (m, 2H), 3.74 (s, 3H), 4.31 (s, 2H), 4.31 (s, 2H), 6.92 (m, 2H), 6.98 (m, 2H), 7.20-7.27 (m, 5H), 7.85 (m, 2H), 8.06 (m, 2H).

Sources & evidence

ORD record
ord-198550b8328d463cbca82764a0296028
Source dataset
uspto-grants-2013_05
Patent number
US08445692B2

Reaction notes

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