Benzyl Bromide → HCID 57422342, compound

HRID 2094914Notes

Reaction equation

HRID 2094914 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([NH:9][S:10]([C:13]2[CH:22]=[CH:21][C:16]([C:17]([O:19]C)=[O:18])=[CH:15][CH:14]=2)(=[O:12])=[O:11])=[CH:5][CH:4]=1.[CH2:23](Br)[C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1>>[CH2:23]([N:9]([C:6]1[CH:7]=[CH:8][C:3]([O:2][CH3:1])=[CH:4][CH:5]=1)[S:10]([C:13]1[CH:14]=[CH:15][C:16]([C:17]([OH:19])=[O:18])=[CH:21][CH:22]=1)(=[O:12])=[O:11])[C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1

Participants

3

Reactant 2

HCID 7498Benzyl BromideHCID 40687864HCID 40687864, compound

Product 1

HCID 57422342HCID 57422342, compound

Procedure

Prepared as in example 5-10 from Methyl 4-(N-(4-methoxyphenyl)sulfamoyl)-benzoate (example 5-35a) and benzyl bromide MS (M−H, 396); 1H NMR (400 MHz, DMSO-d6): δ, ppm: 3.66(s, 3H), 4.75(s, 2H), 6.76(d, J=8 Hz, 2H), 6.90(d, J=8 Hz, 2H), 7.23(m, 5H), 7.74(d, J=8 Hz, 2H), 8.11(d, J=8 Hz, 2H), 13.51(s, 1H).

Sources & evidence

ORD record
ord-81a90d7aee3249269eb63c4cbc10e3cd
Source dataset
uspto-grants-2013_05
Patent number
US08445692B2

Reaction notes

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