HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzaldehyde → N-(1,1-Dimethylethyl)benzenemethanamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzaldehyde | HCID 240 | — |
| Reactant | Tert-Butylamine | HCID 6385 | — |
| Reactant | Cyclohexanecarboxaldehyde | HCID 16275 | — |
| Product | N-(1,1-Dimethylethyl)benzenemethanamine | HCID 76908 | — |
| Product | N-(Cyclohexylmethyl)-2-methylpropan-2-amine | HCID 11469319 | — |
Reaction Steps
In an analogous manner to that in example 1c, except using 4.0% by weight of hydrogenation catalyst, based on the total amount of amine, 1 mol of tert-butylamine was reacted with cyclohexanal (example 3a) or benzaldehyde (example 3b) to give the corresponding secondary amines (tert-butylcyclohexylmethylamine and benzyl-tert-butylamine respectively) which were then analyzed by gas chromatography. For these reactions, yields of 87.3 area % (example 3a) and 14.2 area % (example 3b) of the corresponding secondary amines were achieved.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08445726B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-e72215c3b0a1435aa742430b90c905b2 |
| Source note | uspto-grants-2013_05 |