HuagongsheHuagongshe Chemistry Print Report · For research reference only
Borane → 2-(3-Iodophenyl)ethanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Borane | HCID 6331 | — |
| Reactant | 3-Iodophenylacetic acid | HCID 3870220 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 2-(3-Iodophenyl)ethanol | HCID 15169850 | — |
Reaction Steps
2-(3-Iodophenyl)ethanol was prepared by borane reduction of 3-iodophenylacetic acid in THF in a similar manner as outlined in Example 17, and additionally purified by CC on SiO2 with EtOAc/hexane 2:3.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08445684B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-f644374cd3e04b7e9d5ac825785c44ae |
| Source note | uspto-grants-2013_05 |