Ethylenediamine → 3-[3-(Hydroxymethyl)cyclopentyl]-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]propanenitrile
Reaction equation
[Cl:45][CH2:46][Cl:47].[F:34][C:35]([F:36])([F:37])[C:38]([OH:39])=[O:40].[NH2:41][CH2:42][CH2:43][NH2:44].[OH:1][CH2:2][CH:3]1[CH2:4][CH:5]([CH:8]([CH2:9][C:10]#[N:11])[n:12]2[n:13][cH:14][c:15](-[c:17]3[c:18]4[c:19]([n:20][cH:21][n:22]3)[n:23]([CH2:26][O:27][CH2:28][CH2:29][Si:30]([CH3:31])([CH3:32])[CH3:33])[cH:24][cH:25]4)[cH:16]2)[CH2:6][CH2:7]1>>[OH:1][CH2:2][CH:3]1[CH2:4][CH:5]([CH:8]([CH2:9][C:10]#[N:11])[n:12]2[n:13][cH:14][c:15](-[c:17]3[c:18]4[c:19]([n:20][cH:21][n:22]3)[nH:23][cH:24][cH:25]4)[cH:16]2)[CH2:6][CH2:7]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-33983fba63694a08b7853fd9799b2301
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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