huagongshe.com
HRID2095491

反应详情

EQUATION

反应方程式

HRID 2095491 的结构方程式

REACTANTS

反应物

2
结构：Cl
HCID313

Hydrochloric Acid

ClH

结构：C[C@H]1C(=O)N(CCCC(=O)N2CCC3(CC3)[C@H](O)C2)CCN1C(=O)OCc1ccccc1
HCID67074046

未命名化合物

PRODUCTS

生成物

1
结构：C[C@@H]1NCCN(CCCC(=O)N2CCC3(CC3)[C@H](O)C2)C1=O
HCID67074162

未命名化合物

收率 98%

PROCEDURE

实验过程

In analogy to intermediate 12E, (S)-4-[4-((S)-4-hydroxy-6-aza-spiro[2.5]oct-6-yl)-4-oxo-butyl]-2-methyl-3-oxo-piperazine-1-carboxylic acid benzyl ester was hydrogenated without aqueous HCl to give the titled compound in 98% yield as light yellow oil. MS: 310.2 (MH+).