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HRID2095501

反应详情

EQUATION

反应方程式

HRID 2095501 的结构方程式

REACTANTS

反应物

2
结构：Cl
HCID313

Hydrochloric Acid

ClH

结构：C[C@H]1C(=O)N(CCC(C)(C)C(=O)N2CCC3(CC3)[C@H](O)C2)CCN1C(=O)OCc1ccccc1
HCID67074054

未命名化合物

PRODUCTS

生成物

1
结构：C[C@@H]1NCCN(CCC(C)(C)C(=O)N2CCC3(CC3)[C@H](O)C2)C1=O
HCID67074651

未命名化合物

收率 99%

PROCEDURE

实验过程

In analogy to intermediate 12E, (S)-4-[4-((S)-4-hydroxy-6-aza-spiro[2.5]oct-6-yl)-3,3-dimethyl-4-oxo-butyl]-2-methyl-3-oxo-piperazine-1-carboxylic acid benzyl ester was hydrogenated without aqueous HCl to give the titled compound in 99% yield as light yellow oil. MS: 338.24 (MH+).