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HRID2095551

反应详情

EQUATION

反应方程式

HRID 2095551 的结构方程式

REACTANTS

反应物

2
反应SMILES：CC1(O)CCNCC1
HCID15649174

4-Methylpiperidin-4-ol

C6H13NO

反应SMILES：C[C@H]1C(=O)N(CCC(=O)O)CCN1C(=O)Nc1ccc(Cl)c(Cl)c1
HCID67074220

未命名化合物

2 次

PRODUCTS

产物

1
反应SMILES：C[C@H]1C(=O)N(CCC(=O)N2CCC(C)(O)CC2)CCN1C(=O)Nc1ccc(Cl)c(Cl)c1
HCID58232093

未命名化合物

收率 51%

PROCEDURE

实验过程

In analogy to the procedure described in Example 15, 3-[(S)-4-(3,4-dichloro-phenylcarbamoyl)-3-methyl-2-oxo-piperazin-1-yl]-propionic acid (intermediate 12) and 4-methyl-piperidin-4-ol gave the titled compound in 51% yield as off-white solid. MS: 471.2 (MH+, 2Cl).