HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 66783278, compound → Hydrochloric Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 66783278 | HCID 66783278 | — |
| Reactant | HCID 67074220 | HCID 67074220 | — |
| Product | Hydrochloric Acid | HCID 313 | — |
| Product | HCID 67074419 | HCID 67074419 | — |
Reaction Steps
In analogy to the procedure described in Example 15, 3-[(S)-4-(3,4-dichloro-phenylcarbamoyl)-3-methyl-2-oxo-piperazin-1-yl]-propionic acid (intermediate 12) and 1.1 eq. (3S,5S)-5-methyl-piperidin-3-ol; hydrochloride (intermediate 4) gave the titled compound in 84% yield as off-white solid. MS: 471.3 (MH+, 2Cl).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08445674B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-d934f722c4ff45d7a0a36924db49f837 |
| Source note | uspto-grants-2013_05 |