HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 66783210, compound → Hydrochloric Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 66783210 | HCID 66783210 | — |
| Reactant | HCID 67074220 | HCID 67074220 | — |
| Product | Hydrochloric Acid | HCID 313 | — |
| Product | HCID 58232151 | HCID 58232151 | — |
Reaction Steps
In analogy to the procedure described in Example 15, 3-[(S)-4-(3,4-dichloro-phenylcarbamoyl)-3-methyl-2-oxo-piperazin-1-yl]-propionic acid (intermediate 12) and 1.1 eq. (3S,4S)-4-methyl-piperidin-3-ol; hydrochloride (intermediate 3) gave the titled compound in 84% yield as off-white solid. MS: 471.3 (MH+, 2Cl).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08445674B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-a8d09c1b4ac84cf29443a8e02c8cdac8 |
| Source note | uspto-grants-2013_05 |