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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2095555Generated: October 31, 2026

4-(Trifluoromethyl)piperidine hydrochloride → HCID 67074663, compound

https://huagongshe.com/reaction/2095555

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Trifluoromethyl)piperidine hydrochlorideHCID 16218160—
ReactantHCID 67074220HCID 67074220—
ProductHCID 67074663HCID 6707466331%

Reaction Steps

In analogy to the procedure described in Example 15, 3-[(S)-4-(3,4-dichloro-phenylcarbamoyl)-3-methyl-2-oxo-piperazin-1-yl]-propionic acid (intermediate 12) and 4-trifluoromethyl-piperidine hydrochloride gave the titled compound in 31% yield as white foam. MS: 509.13 (MH+, 2Cl).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08445674B2
Source datasetuspto-grants-2013_05
ORD IDord-d128ea02f7ab4ae28eda61ae15b4c46f
Source noteuspto-grants-2013_05