HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(TrifluoroMethoxy)phenyl isocyanate → HCID 67086994, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(TrifluoroMethoxy)phenyl isocyanate | HCID 20067555 | — |
| Reactant | HCID 67074162 | HCID 67074162 | — |
| Product | HCID 67086994 | HCID 67086994 | 70% |
Reaction Steps
In analogy to the procedure described in Example 30, (S)-1-[4-((S)-4-hydroxy-6-aza-spiro[2.5]oct-6-yl)-4-oxo-butyl]-3-methyl-piperazin-2-one (intermediate 13) and 1-isocyanato-3-trifluoromethoxy-benzene (intermediate 15) gave the titled compound in 70% yield as white amorphous solid. MS: 513.23 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08445674B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-873a3be339044784a12e23f0903e10f1 |
| Source note | uspto-grants-2013_05 |