HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 67074162, compound → HCID 67086935, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 67074162 | HCID 67074162 | — |
| Reactant | HCID 86652696 | HCID 86652696 | — |
| Product | HCID 67086935 | HCID 67086935 | 67% |
Reaction Steps
In analogy to the procedure described in Example 30, (S)-1-[4-((S)-4-hydroxy-6-aza-spiro[2.5]oct-6-yl)-4-oxo-butyl]-3-methyl-piperazin-2-one (intermediate 13) and 1-chloro-4-isocyanato-2-trifluoromethoxy-benzene (intermediate 18) gave the titled compound in 67% yield as light brown foam. MS: 547.19 (MH+, 1Cl).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08445674B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-9bed9e4cf6cf4656baea414878212528 |
| Source note | uspto-grants-2013_05 |