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HRID2095592

反应详情

EQUATION

反应方程式

HRID 2095592 的结构方程式

REACTANTS

反应物

2
结构：[BH4-].[Li+]
HCID4148881

Lithium borohydride

BH4Li

结构：COC(=O)CN(CCC(=O)OC(C)(C)C)c1ccc(C(F)(F)F)c(Cl)c1
HCID67074349

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)CCN(CCO)c1ccc(C(F)(F)F)c(Cl)c1
HCID67074459

未命名化合物

收率 84%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CO
溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

In analogy to the procedure described for intermediate 40C, 3-[(3-chloro-4-trifluoromethyl-phenyl)-methoxycarbonylmethyl-amino]-propionic acid tert-butyl ester and LiBH4 (2 M in THF)/MeOH gave the title compound in 84% yield as yellow oil. MS: 368.12 (MH+, Cl).