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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2095815Generated: November 2, 2026

Tetrahydrofuran → HCID 58158612, compound

https://huagongshe.com/reaction/2095815

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantSodium HydroxideHCID 14798—
ReactantHCID 58158541HCID 58158541—
SolventMethanolHCID 887—
ProductHCID 58158612HCID 5815861292%

Reaction Steps

In the same manner as in Reference Example 65 and using ethyl 2-(2-chlorophenyl)-1-methyl-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylate (2.8 g, 9.9 mmol), tetrahydrofuran (6 mL), methanol (5 mL) and 4N aqueous sodium hydroxide solution (8 mL) as starting materials, the title compound (2.3 g, 91%) was obtained as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08445509B2
Source datasetuspto-grants-2013_05
ORD IDord-e59c68ca752041df8ce6b18d34c8fb8d
Source noteuspto-grants-2013_05