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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2095816Generated: November 4, 2026

Diethyl (ethoxymethylene)malonate → HCID 58158459, compound

https://huagongshe.com/reaction/2095816

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethyl (ethoxymethylene)malonateHCID 6871—
ReactantPotassium CarbonateHCID 11430—
Reactant2,4-Difluorophenylhydrazine hydrochlorideHCID 2733301—
SolventWaterHCID 962—
ProductHCID 58158459HCID 5815845966.6%

Reaction Steps

In the same manner as in Reference Example 63 and using (2,4-difluorophenyl)hydrazine•hydrochloride (5.1 g, 28 mmol), water (100 mL), potassium carbonate (8.6 g, 62 mmol) and diethyl ethoxymethylenemalonate (7.4 g, 34 mmol) as starting materials, the title compound (5.0 g, 66%) was obtained as a pale-yellow solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08445509B2
Source datasetuspto-grants-2013_05
ORD IDord-3263d2b169034d7395a46cfbdb7acc57
Source noteuspto-grants-2013_05