Tetrahydrofuran → (+/-)-5-Bromo-1,3-dihydrospiro[indene-2,3'-indol]-2'(1'H)-one
Reaction equation
[Br:16][c:17]1[cH:18][c:19]([CH2:25][Br:26])[c:20]([CH2:23][Br:24])[cH:21][cH:22]1.[CH2:27]1[O:28][CH2:29][CH2:30][CH2:31]1.[Li:11][CH2:12][CH2:13][CH2:14][CH3:15].[NH:1]1[C:2](=[O:10])[CH2:3][c:4]2[cH:5][cH:6][cH:7][cH:8][c:9]21>>[NH:1]1[C:2](=[O:10])[C:3]2([c:4]3[cH:5][cH:6][cH:7][cH:8][c:9]31)[CH2:23][c:20]1[c:19]([cH:18][c:17]([Br:16])[cH:22][cH:21]1)[CH2:25]2Participants
5
Sources & evidence
- ORD record
- ord-0922b4fd439d4d6f806c355054a746c9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
Loading…