HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 86642252, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 59361626 | HCID 59361626 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 86642252 | HCID 86642252 | — |
Reaction Steps
{1-[4-Hydroxy-4-(6-methoxy-pyridin-3-yl)-cyclohexyl]-azetidin-3-yl}-carbamic acid tert-butyl ester (less polar isomer from Step A, 5.50 g, 14.6 mmol) in DCM (10 mL) and TFA (10 mL) at room temperature was stirred for 2 hours. The solvent was removed and dried under vacuum to give the title compound as colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08450304B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-976ea85e2b3646dc98a3963c56d339f3 |
| Source note | uspto-grants-2013_05 |