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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2096167Generated: November 1, 2026

1,3-Benzodioxole-5-carbonyl chloride → HCID 46241830, compound

https://huagongshe.com/reaction/2096167

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,3-Benzodioxole-5-carbonyl chlorideHCID 2734749—
Reactant2-amino-N-{1-[4-hydroxy-4-(6-methoxy-pyridin-3-yl)-cyclohexyl]-azetidin-3-yl}-acetamideHCID 59361557—
ProductHCID 46241830HCID 46241830—

Reaction Steps

The title compound was prepared as yellow solid from coupling of 2-amino-N-{1-[4-hydroxy-4-(6-methoxy-pyridin-3-yl)-cyclohexyl]-azetidin-3-yl}-acetamide, as prepared in Step D of Example 16, and piperonoyl chloride (Aldrich) using the procedure described in Example 18.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08450304B2
Source datasetuspto-grants-2013_05
ORD IDord-eda09f29eb754e06a1c2d5be9cdf462c
Source noteuspto-grants-2013_05