HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,4-Dioxaspiro[4.5]decan-8-one → 8-(1-Methyl-1H-imidazol-2-yl)-1,4-dioxa-spiro[4.5]decan-8-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,4-Dioxaspiro[4.5]decan-8-one | HCID 567415 | — |
| Reactant | 2-Bromo-1-methyl-1H-imidazole | HCID 2773262 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 8-(1-Methyl-1H-imidazol-2-yl)-1,4-dioxa-spiro[4.5]decan-8-ol | HCID 59361582 | — |
Reaction Steps
The title compound was prepared as a white solid from 2-bromo-1-methyl-1H-imidazole (Aldrich) and 1,4-dioxa-spiro[4.5]decan-8-one in THF using the procedure described in Step A of Example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08450304B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-4925b5b0b958480383dc6babf696d132 |
| Source note | uspto-grants-2013_05 |