1H-Pyrazole, 4-bromo-1-methyl- → HCID 59361588, compound

HRID 2096182Notes

Reaction equation

HRID 2096182 reaction equation
[Br:1][C:2]1[CH:3]=[N:4][N:5]([CH3:7])[CH:6]=1.[O:8]1[C:12]2([CH2:17][CH2:16][C:15](=[O:18])[CH2:14][CH2:13]2)[O:11][CH2:10][CH2:9]1>C1COCC1>[Br:1][C:2]1[C:3]([C:15]2([OH:18])[CH2:16][CH2:17][C:12]3([O:11][CH2:10][CH2:9][O:8]3)[CH2:13][CH2:14]2)=[N:4][N:5]([CH3:7])[CH:6]=1

Participants

4

Reactant 2

HCID 1674331H-Pyrazole, 4-bromo-1-methyl-HCID 5674151,4-Dioxaspiro[4.5]decan-8-one

Product 1

HCID 59361588HCID 59361588, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

The title compound was prepared as a white solid from 4-bromo-1-methyl-1H-pyrazole, as prepared in the previous step, and 1,4-dioxa-spiro[4.5]decan-8-one in THF using the procedure described in Step A of Example 1.

Sources & evidence

ORD record
ord-aa6f5efa88bc418c903942b99d90f4cd
Source dataset
uspto-grants-2013_05
Patent number
US08450304B2

Reaction notes

Loading…