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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2096220Generated: October 26, 2026

Isothiazole → 8-Isothiazol-5-yl-1,4-dioxa-spiro[4.5]decan-8-ol

https://huagongshe.com/reaction/2096220

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsothiazoleHCID 67515—
Reactant1,4-Dioxaspiro[4.5]decan-8-oneHCID 567415—
Product8-Isothiazol-5-yl-1,4-dioxa-spiro[4.5]decan-8-olHCID 59361591—

Reaction Steps

The title compound was prepared as a white solid from isothiazole (Focus Synthesis) and 1,4-dioxa-spiro[4.5]decan-8-one using the procedure described in Step A of Example 33.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08450304B2
Source datasetuspto-grants-2013_05
ORD IDord-f9163bee0dc24103bb1ba65913e5710f
Source noteuspto-grants-2013_05