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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2096234Generated: November 2, 2026

Trifluoroacetic acid → N-(Azetidin-3-ylcarbamoylmethyl)-3,5-bis-trifluoromethyl-benzamide TFA salt

https://huagongshe.com/reaction/2096234

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 59361639HCID 59361639—
ProductN-(Azetidin-3-ylcarbamoylmethyl)-3,5-bis-trifluoromethyl-benzamide TFA saltHCID 86642254—

Reaction Steps

The title compound was prepared as colorless oil from TFA de-protection of 3-[2-(3,5-bis-trifluoromethyl-benzoylamino)-acetylamino]-azetidine-1-carboxylic acid tert-butylester, as prepared in the previous step, using the procedure described in Step D of Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08450304B2
Source datasetuspto-grants-2013_05
ORD IDord-2c928749b89946e9bca6233df85baceb
Source noteuspto-grants-2013_05