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HRID2096236

反应详情

EQUATION

反应方程式

HRID 2096236 的结构方程式

REACTANTS

反应物

3
结构：CCN=C=NCCCN(C)C
HCID15908

1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimide

C8H17N3

结构：CC(C)(C)OC(=O)N1CC(N)C1
HCID1516507

1-Boc-3-(amino)azetidine

C8H16N2O2

结构：O=C(O)CNC(=O)c1cc(C(F)(F)F)ccc1C(F)(F)F
HCID86642255

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)N1CC(NC(=O)CNC(=O)c2cc(C(F)(F)F)ccc2C(F)(F)F)C1
HCID59361607

未命名化合物

PROCEDURE

实验过程

The title compounds were prepared as white solids from EDCI coupling between 3-amino-azetidine-1-carboxylic acid tert-butyl ester and (2,5-bistrifluoromethyl-benzoylamino)-acetic acid (prepared by the method similar to Ingersoll, A. W. et. al., Organic Syntheses 1932, XII, 40-2) using the procedure described in Step C of Example 1.

WORKUP

后处理

  1. customprepared by the method similar to Ingersoll