HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 59361627, compound → 2-Chloro-N-({1-[4-hydroxy-4-(6-methyl-pyridin-3-yl)-cyclohexyl]-azetidin-3-ylcarbamoyl}-methyl)-5-trifluoromethyl-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 59361627 | HCID 59361627 | — |
| Reactant | N-(azetidin-3-ylcarbamoylmethyl)-2-chloro-5-trifluoromethyl-benzamide | HCID 59361638 | — |
| Product | 2-Chloro-N-({1-[4-hydroxy-4-(6-methyl-pyridin-3-yl)-cyclohexyl]-azetidin-3-ylcarbamoyl}-methyl)-5-trifluoromethyl-benzamide | HCID 46241322 | — |
Reaction Steps
The title compounds were prepared as white solids from reductive amination of 4-hydroxy-4-(6-methyl-pyridin-3-yl)-cyclohexanone, as prepared in Example 13 Step B, and N-(azetidin-3-ylcarbamoylmethyl)-2-chloro-5-trifluoromethyl-benzamide using the procedure described in Step E of Example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08450304B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-e35efa01a4774021a8c7f42e591716cd |
| Source note | uspto-grants-2013_05 |