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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 209632Generated: October 31, 2026

Dichloromethane → tert-Butyl 4-(2-(4-(2-fluoro-4-(3-(2-(4-fluorophenyl)acetyl)ureido)phenoxy)pyridin-3-yl)ethynyl)cyclohex-3-enylcarbamate

https://huagongshe.com/reaction/209632

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
Reactant1-(4-(6-(4-Methoxybenzylamino)pyrimidin-4-yloxy)-3-fluorophenyl)-3-(2-(4-fluorophenyl)acetyl)ureaHCID 11569893—
Reactant2-(4-Fluorophenyl)acetyl isocyanateHCID 23153088—
Reactanttert-Butyl 4-(2-(4-(4-amino-2-fluorophenoxy)pyridin-3-yl)ethynyl)cyclohex-3-enylcarbamateHCID 59853058—
Producttert-Butyl 4-(2-(4-(2-fluoro-4-(3-(2-(4-fluorophenyl)acetyl)ureido)phenoxy)pyridin-3-yl)ethynyl)cyclohex-3-enylcarbamateHCID 59852858—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-ef83b684938c4322a3b0edf7b62b304f
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)