HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Bromo-2-phenylpyrimidine → phenyl(5-(2-(pyridin-3-yl)-1H-imidazol-5-yl)pyrimidin-2-yl)methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Bromo-2-phenylpyrimidine | HCID 14387745 | — |
| Reactant | (5-Bromo-pyrimidine-2-yl)-phenyl-methanone | HCID 67360359 | — |
| Reactant | 3-(1-benzyl-1H-imidazol-2-yl)pyridine | HCID 67361568 | — |
| Product | phenyl(5-(2-(pyridin-3-yl)-1H-imidazol-5-yl)pyrimidin-2-yl)methanone | HCID 59252386 | — |
Reaction Steps
The title compound is prepared by the method described in Example 1, except that (5-bromopyrimidin-2-yl)(phenyl)methanone (prepared according to the procedure described in WO 2008/121670 p. 94) is used instead of 5-bromo-2-phenylpyrimidine and 3-(1-benzyl-1H-imidazol-2-yl)pyridine is used instead of 1-benzyl-2-phenyl-1H-imidazole in Step C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08450326B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-70eebdc67b8a4233a8d29db87f518dba |
| Source note | uspto-grants-2013_05 |