Phenylboronic Acid → HCID 44554659, compound

HRID 2096675Notes

Reaction equation

Cl[C:2]1[C:3]2[N:11]=[N:10][N:9]([CH2:12][C:13]3[CH:18]=[CH:17][CH:16]=[C:15]([C:19]4([OH:23])[CH2:22][CH2:21][CH2:20]4)[N:14]=3)[C:4]=2[N:5]=[C:6]([NH2:8])[N:7]=1.[C:24]1(B(O)O)[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1>>[OH:23][C:19]1([C:15]2[N:14]=[C:13]([CH2:12][N:9]3[C:4]4[N:5]=[C:6]([NH2:8])[N:7]=[C:2]([C:24]5[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=5)[C:3]=4[N:11]=[N:10]3)[CH:18]=[CH:17][CH:16]=2)[CH2:22][CH2:21][CH2:20]1

Participants

Reactant 2

HCID 66827Phenylboronic Acid

HCID 86655319HCID 86655319, compound

Product 1

HCID 44554659HCID 44554659, compound

Procedure

Prepared from 7-chloro-3-{6-[1-hydroxy-1-cyclobutyl]pyridin-2-ylmethyl}-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-ylamine and phenylboronic acid by the method described in Example 7 to give the title compound (0.03 g).

Sources & evidence

ORD record: ord-c98c64629570404e926bd63e3a6d9e83
Source dataset: uspto-grants-2013_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08450328B2

Reaction notes

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