HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 66905887, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 59161742 | HCID 59161742 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 66905887 | HCID 66905887 | — |
Reaction Steps
To tert-butyl 4-(isoquinolin-6-ylamino)-4-oxo-1-(thiophen-3-yl)butylcarbamate (E73E) in CH2Cl2 is added HCl (4N in dioxane), and the solution is stirred for 8 hours. The solvents are evaporated to give 4-amino-N-(isoquinolin-6-yl)-4-(thiophen-3-yl)butanamide dihydrochloride (E73).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08450344B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-27b39a418de74cefaab04d6a237b5d18 |
| Source note | uspto-grants-2013_05 |