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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2097471Generated: November 1, 2026

Isopropyl iodide → 4-Bromo-1-methoxy-2-[(propan-2-yl)oxy]benzene

https://huagongshe.com/reaction/2097471

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsopropyl iodideHCID 6362—
Reactant5-Bromo-2-methoxyphenolHCID 142228—
Product4-Bromo-1-methoxy-2-[(propan-2-yl)oxy]benzeneHCID 4673895286%

Reaction Steps

Reaction and post treatment were carried out in the same manner as in Reference Example 7-(a) except for using 10.1 g (49.8 mmol) of 5-bromo-2-methoxyphenol, and using 15 ml of isopropyl iodide in place of 1-bromo-2-chloroethane, whereby 10.4 g of the title compound was obtained as a pale yellowish solid. (Yield: 86%)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08450319B2
Source datasetuspto-grants-2013_05
ORD IDord-a32da5b587a54276a8e4474713d739eb
Source noteuspto-grants-2013_05