Hydrochloric Acid → 2-[(piperidin-4-ylmethyl)-amino]-1H-benzimidazole-4-carboxylic acid (2-methoxy-ethyl)-amide

HRID 209767Notes

Reaction equation

HRID 209767 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][CH:11]([CH2:14][NH:15][c:16]2[n:17][c:18]3[c:19]([nH:20]2)[cH:21][cH:22][cH:23][c:24]3[C:25]([NH:26][CH2:27][CH2:28][O:29][CH3:30])=[O:31])[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[CH3:39][OH:40].[ClH:38].[O:32]1[CH2:33][CH2:34][O:35][CH2:36][CH2:37]1>>[NH:8]1[CH2:9][CH2:10][CH:11]([CH2:14][NH:15][c:16]2[n:17][c:18]3[c:19]([nH:20]2)[cH:21][cH:22][cH:23][c:24]3[C:25]([NH:26][CH2:27][CH2:28][O:29][CH3:30])=[O:31])[CH2:12][CH2:13]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 887MethanolHCID 312751,4-DioxaneHCID 690661524-{[4-(2-methoxy-ethylcarbamoyl)-1H-benzimidazol-2-ylamino)-methyl}-piperidine-1-carboxylic acid tert-butyl ester

Product 1

HCID 866105062-[(piperidin-4-ylmethyl)-amino]-1H-benzimidazole-4-carboxylic acid (2-methoxy-ethyl)-amide

Sources & evidence

ORD record
ord-9ea760087a074367aca72ba25d1f60d9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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