4-Methoxyphenylacetic Acid → HCID 897877, compound

HRID 2097968Notes

Reaction equation

HRID 2097968 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH2:9][C:10]([OH:12])=O)=[CH:5][CH:4]=1.[NH2:13][C:14]1[CH:18]=[CH:17][S:16][C:15]=1[C:19]([O:21][CH3:22])=[O:20]>>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([CH2:9][C:10]([NH:13][C:14]2[CH:18]=[CH:17][S:16][C:15]=2[C:19]([O:21][CH3:22])=[O:20])=[O:12])=[CH:7][CH:8]=1

Participants

3

Reactant 2

HCID 76904-Methoxyphenylacetic AcidHCID 89652Methyl 3-amino-2-thiophenecarboxylate

Product 1

HCID 897877HCID 897877, compound

Procedure

The title compound was prepared from 2-(4-methoxyphenyl)acetic acid (3.18 g, 19.2 mmol) and methyl 3-aminothiophene-2-carboxylate (3.02 g, 19.2 mmol) according to protocol B. Retention time (min)=2.143, method [1], MS (ESI) 306.1 (M+H).

Sources & evidence

ORD record
ord-5c34640706a24fb093d6c78a90ec31e7
Source dataset
uspto-grants-2013_05
Patent number
US08450363B2

Reaction notes

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