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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2098020Generated: October 31, 2026

4-bromo-3-(4H-1,2,4-triazol-3-yl)thiophen-2-amine → HCID 56665246, compound

https://huagongshe.com/reaction/2098020

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-bromo-3-(4H-1,2,4-triazol-3-yl)thiophen-2-amineHCID 59636686—
ReactantHCID 68785189HCID 68785189—
ProductHCID 56665246HCID 56665246—

Reaction Steps

The title compound was prepared from 2-(2-oxo-7-(trifluoromethyl)-1,6-naphthyridin-1(2H)-yl)acetic acid (55 mg, 0.203 mmol) and 4-bromo-3-(1H-1,2,4-triazol-5-yl)thiophen-2-amine (25 mg, 0.102 mmol) according to protocol A. Retention time (min)=4.505, method [7], MS (ESI) 499.0 (M+H); 1H NMR (300 MHz, CD3OD) δ 9.06 (s, 1H), 8.31 (s, 1H), 8.24 (d, J=9.4 Hz, 1H), 7.94 (s, 1H), 7.14 (s, 1H), 6.99 (d, J=9.4 Hz, 1H), 5.39 (s, 2H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08450363B2
Source datasetuspto-grants-2013_05
ORD IDord-7cb2fde21c8941c1b9e64f8e426b5d74
Source noteuspto-grants-2013_05