HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Thiazol-4-yl)thiophen-3-amine → HCID 68784811, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Thiazol-4-yl)thiophen-3-amine | HCID 68755362 | — |
| Reactant | 2-(2-oxo-6-(trifluoromethyl)quinolin-1(2H)-yl)acetic acid | HCID 68759857 | — |
| Product | HCID 68784811 | HCID 68784811 | — |
Reaction Steps
The title compound was prepared from 2-(thiazol-4-yl)thiophen-3-amine and 2-(2-oxo-6-(trifluoromethyl)quinolin-1(2H)-yl)acetic acid according to protocol A. Retention time (min)=6.485, method [7], MS (ESI) 436.1 (M+H); 1H NMR (300 MHz, CD3C1) δ 11.32 (s, 1H), 8.51 (d, J=1.5 Hz, 1H), 8.04 (d, J=5.5 Hz, 1H), 7.92 (d, J=10.2 Hz, 1H), 7.90 (s, 1H), 7.80 (d, J=8.9 Hz, 1H), 7.50 (d, J=8.9 Hz, 1H), 7.22 (d, J=1.4 Hz, 1H), 7.20 (d, J=5.5 Hz, 1H), 7.03 (d, J=9.7 Hz, 1H), 5.23 (s, 2H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08450363B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-97ef9a72f01f43fcac95db732cc34588 |
| Source note | uspto-grants-2013_05 |