Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2098165Generated: October 26, 2026

1-Naphthaleneacetic Acid → Methyl 3-(2-(naphthalen-1-yl)acetamido)thiophene-2-carboxylate

https://huagongshe.com/reaction/2098165

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Naphthaleneacetic AcidHCID 6862—
ReactantMethyl 3-amino-2-thiophenecarboxylateHCID 89652—
ProductMethyl 3-(2-(naphthalen-1-yl)acetamido)thiophene-2-carboxylateHCID 25660569—

Reaction Steps

Methyl 3-(2-(naphthalen-1-yl)acetamido)thiophene-2-carboxylate was prepared from methyl 3-aminothiophene-2-carboxylate (4.30 g, 27.3 mmol) and 2-(naphthalen-1-yl)acetic acid (3.10 g, 27.3 mmol) according to protocol A. Retention time (min)=8.738, method [7], MS (ESI) 326.1 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08450363B2
Source datasetuspto-grants-2013_05
ORD IDord-22b0eb4bac4a4c85baf38fe371815ca6
Source noteuspto-grants-2013_05