Cyclopropanecarbonyl chloride → HCID 86618391, compound

HRID 2098669Notes

Reaction equation

HRID 2098669 reaction equation
[Cl:1][C:2]1[N:3]=[C:4]([N:12]2[CH2:17][CH2:16][O:15][CH2:14][CH2:13]2)[C:5]2[S:10][C:9]([NH2:11])=[CH:8][C:6]=2[N:7]=1.[CH:18]1([C:21](Cl)=[O:22])[CH2:20][CH2:19]1>>[Cl:1][C:2]1[N:3]=[C:4]([N:12]2[CH2:17][CH2:16][O:15][CH2:14][CH2:13]2)[C:5]2[S:10][C:9]([NH:11][C:21]([CH:18]3[CH2:20][CH2:19]3)=[O:22])=[CH:8][C:6]=2[N:7]=1

Participants

3

Reactant 2

HCID 77637Cyclopropanecarbonyl chlorideHCID 595928682-Chloro-4-morpholinothieno[3,2-d]pyrimidin-6-amine

Product 1

HCID 86618391HCID 86618391, compound

Procedure

2-Chloro-4-morpholinothieno[3,2-d]pyrimidin-6-amine (40 mg) was reacted with 27 μL of cyclopropanecarbonyl chloride via General Procedure G to give N-(2-chloro-4-morpholinothieno[3,2-d]pyrimidin-6-yl)cyclopropanecarboxamide.

Sources & evidence

ORD record
ord-a659b4d0986e440e8b670d9e7e4d266a
Source dataset
uspto-grants-2013_05
Patent number
US08450315B2

Reaction notes

Loading…