HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → HCID 178482580, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | 2-Chloro-4-morpholinothieno[3,2-d]pyrimidine-6-carbaldehyde | HCID 45789985 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 178482580 | HCID 178482580 | — |
Reaction Steps
To 2-chloro-4-morpholin-4-yl-thieno[3,2-d]pyrimidine-6-carbaldehyde 10 (1.0 g) in methanol under nitrogen was added methylamine solution (11.79 g methylamine in 50 ml methanol) (1.39 ml). The reaction mixture was stirred at room temperature overnight. The solvents were then removed in vacuo to yield [1-(2-Chloro-4-morpholin-4-yl-thieno[3,2-d]pyrimidin-6-yl)-meth-(E)-ylidene]-methyl-amine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08450315B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-c825cfa2d80e49c099d853db601b0220 |
| Source note | uspto-grants-2013_05 |