HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2098839Generated: October 30, 2026
Sodium Iodide → 3-iodo-N,N-dimethylpropane-1-sulfonamide
https://huagongshe.com/reaction/2098839
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sodium Iodide | HCID 5238 | — |
| Reactant | 3-chloro-N,N-dimethylpropane-1-sulfonamide | HCID 10035328 | — |
| Solvent | Methyl Ethyl Ketone | HCID 6569 | — |
| Product | 3-iodo-N,N-dimethylpropane-1-sulfonamide | HCID 86240421 | — |
Reaction Steps
A mixture of 3-chloro-propane-1-sulfonic acid dimethylamide (1.06 g) and sodium iodide (2.57 g) in 2-butanone (20 mL) was heated at 80° C. for 16 h. After cooling to room temperature the solvent was reduced in vacuo. The residue was partitioned between ethyl acetate (20 mL) and water (20 mL). The organic layer was dried (MgSO4) and reduced in vacuo to give 3-iodo-propane-1-sulfonic acid dimethylamide as a yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08450315B2 |
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| Source dataset | uspto-grants-2013_05 |
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| ORD ID | ord-1e3754eba3d04522949c2e122ae15ca4 |
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| Source note | uspto-grants-2013_05 |
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