反应详情

To a stirred solution of methyl 4-hydroxy-3-(2-methylprop-1-enyl)benzoate T13.2 (0.320 g, 1.6 mmol) in EtOAc (2.00 mL, 20 mmol) at 23° C. was added palladium on carbon (0.017 g, 0.16 mmol). The reaction was stirred under an atmosphere of hydrogen (0.0031 g, 1.6 mmol) for 16 hours. The reaction mixture was then filtered and concentrated in vacuo to give a clear oil. The residue was purified on silica gel (0-20% EtOAc in hexanes) to yield T13.3 as a colorless oil (0.256 g, 79% yield)

1. filtrationThe reaction mixture was then filtered
2. concentrationconcentrated in vacuo
3. customto give a clear oil
4. customThe residue was purified on silica gel (0-20% EtOAc in hexanes)