HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 1-[2-Chloro-4-(trifluoromethoxy)phenyl]methanamine--hydrogen chloride (1/1)
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 2-Chloro-4-(trifluoromethoxy)benzonitrile | HCID 66861019 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 1-[2-Chloro-4-(trifluoromethoxy)phenyl]methanamine--hydrogen chloride (1/1) | HCID 66861522 | — |
Reaction Steps
The preparation takes place in analogy to Example 6A from the compound from Example 3A with subsequent treatment with 4N hydrochloric acid in dioxane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07569563B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-403702ddbcae4f0c98f5bedeae697e1c |
| Source note | uspto-grants-2009_08 |