Hydrochloric Acid → 2,4-Dichloro-6-methylbenzylamine hydrochloride

HRID 2099313Notes

Reaction equation

HRID 2099313 reaction equation
[Cl:1][C:2]1[CH:9]=[C:8]([Cl:10])[CH:7]=[C:6]([CH3:11])[C:3]=1[C:4]#[N:5].Cl>O1CCOCC1>[ClH:1].[Cl:1][C:2]1[CH:9]=[C:8]([Cl:10])[CH:7]=[C:6]([CH3:11])[C:3]=1[CH2:4][NH2:5]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 28009652,4-Dichloro-6-methylbenzonitrile

Product 1

HCID 467858042,4-Dichloro-6-methylbenzylamine hydrochloride

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

The preparation takes place in analogy to Example 6A from 2,4-dichloro-6-methylbenzonitrile with subsequent treatment with 4N hydrochloric acid in dioxane.

Sources & evidence

ORD record
ord-138cfb41756f4ae0a67635a0072d0ffb
Source dataset
uspto-grants-2009_08
Patent number
US07569563B2

Reaction notes

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