HCID 53904438, compound → HCID 86585678, compound

HRID 2099343Notes

Reaction equation

HRID 2099343 reaction equation
COCCS(F)(F)([F:11])(CCOC)N.[F:14][C:15]1[CH:41]=[CH:40][C:18]([C:19]([C:33]2[CH:38]=[CH:37][C:36]([F:39])=[CH:35][CH:34]=2)(O)[C:20]([O:22][C@@:23]23[N:30]([CH3:31])[C@@H:27]([CH2:28][CH2:29]2)[CH2:26][CH:25]=[CH:24]3)=[O:21])=[CH:17][CH:16]=1>ClCCl>[C@@:23]12([OH:22])[N:30]([CH3:31])[C@@H:27]([CH2:28][CH2:29]1)[CH2:26][CH:25]=[CH:24]2.[F:11][C:19]([C:33]1[CH:38]=[CH:37][C:36]([F:39])=[CH:35][CH:34]=1)([C:18]1[CH:40]=[CH:41][C:15]([F:14])=[CH:16][CH:17]=1)[C:20]([O-:22])=[O:21]

Participants

4

Reactant 2

HCID 53904438HCID 53904438, compoundHCID 86585677Tropenol 4,4'-difluorobenzilate

Product 1

HCID 86585678HCID 86585678, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

2.94 g (0.013 mol) of bis-(2-methoxyethyl)-aminosulfur trifluoride are reacted with 3.85 g (0.01 mol) of 5d analogously to Example 4, step 4.3 in 100 mL of dichloromethane. The product is recrystallized from acetonitrile in the form of its hydrochloride. Yield: 2.93 g (69% of theory).

Workup

  1. customThe product is recrystallized from acetonitrile in the form of its hydrochloride

Sources & evidence

ORD record
ord-370f8c352a01470fa6ebc33e5e62d449
Source dataset
uspto-grants-2009_08
Patent number
US07569581B2

Reaction notes

Loading…