HuagongsheHuagongshe Chemistry Print Report · For research reference only
(Bis(2-methoxyethyl)amino)sulfur trifluoride → Tropenol 2-fluoro-2,2-diphenylacetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (Bis(2-methoxyethyl)amino)sulfur trifluoride | HCID 2734690 | — |
| Reactant | Tropenol benzilate | HCID 86585680 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | Tropenol 2-fluoro-2,2-diphenylacetate | HCID 86585679 | — |
Reaction Steps
15.86 mL (0.086 mol) of bis-(2-methoxyethyl)aminosulfur trifluoride is reacted with 25 g (0.072 mol) of 5f analogously to Example 4, step 4.3 in 480 mL of chloroform. The product is recrystallized from acetone in the form of its hydrochloride. Yield: 18.6 g of white crystals (67% of theory); melting point: 181° C.-182° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07569581B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-f527263ee5e74af3aee870cbd0c50f1c |
| Source note | uspto-grants-2009_08 |