Bicarbonate Ion → N-{6-[5-(Aminosulfonyl)-3-pyridinyl]-1H-indazol-4-yl}-2-methyl-1,3-thiazole-4-carboxamide
Reaction equation
[Br:28][c:29]1[cH:30][c:31]([S:35](=[O:36])(=[O:37])[NH2:38])[cH:32][n:33][cH:34]1.[C:43](=[O:44])([OH:45])[O-:46].[CH3:1][c:2]1[s:3][cH:4][c:5]([C:7](=[O:8])[NH:9][c:10]2[c:11]3[cH:12][n:13][nH:14][c:15]3[cH:16][c:17]([B:19]3[O:20][C:21]([CH3:22])([CH3:23])[C:24]([CH3:25])([CH3:26])[O:27]3)[cH:18]2)[n:6]1.[CH:39]([OH:40])([CH3:41])[CH3:42].[Na+:47].[cH:48]1[cH:49][cH:50][c:51]([P:52]([Pd:53]([P:54]([c:55]2[cH:56][cH:57][cH:58][cH:59][cH:60]2)([c:61]2[cH:62][cH:63][cH:64][cH:65][cH:66]2)[c:67]2[cH:68][cH:69][cH:70][cH:71][cH:72]2)([P:73]([c:74]2[cH:75][cH:76][cH:77][cH:78][cH:79]2)([c:80]2[cH:81][cH:82][cH:83][cH:84][cH:85]2)[c:86]2[cH:87][cH:88][cH:89][cH:90][cH:91]2)[P:92]([c:93]2[cH:94][cH:95][cH:96][cH:97][cH:98]2)([c:99]2[cH:100][cH:101][cH:102][cH:103][cH:104]2)[c:105]2[cH:106][cH:107][cH:108][cH:109][cH:110]2)([c:111]2[cH:112][cH:113][cH:114][cH:115][cH:116]2)[c:117]2[cH:118][cH:119][cH:120][cH:121][cH:122]2)[cH:123][cH:124]1>>[CH3:1][c:2]1[s:3][cH:4][c:5]([C:7](=[O:8])[NH:9][c:10]2[c:11]3[cH:12][n:13][nH:14][c:15]3[cH:16][c:17](-[c:29]3[cH:30][c:31]([S:35](=[O:36])(=[O:37])[NH2:38])[cH:32][n:33][cH:34]3)[cH:18]2)[n:6]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-60c0e2eff62a4d8ab8fc785791d46d8e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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