HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Toluenesulfonic acid → HCID 57289826, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Toluenesulfonic acid | HCID 6101 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | HCID 68856341 | HCID 68856341 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 57289826 | HCID 57289826 | — |
Reaction Steps
20.4 g of 5-butoxy-3-(4-methoxybenzoyl)-2-isoxazoline and 1.4 g of p-toluenesulfonic acid in 200 ml of toluene are stirred under reflux for 8 hours. Stirring with 50 ml of sodium hydrogen carbonate solution is then carried out and the aqueous phase is separated off. After concentration of the organic phase and purification over silica gel, 3-(4-methoxybenzoyl)isoxazole is obtained in the form of colourless crystals, m.p: 71-73° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07569727B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-9abf016bbf22417ba9180bf94e3ad67e |
| Source note | uspto-grants-2009_08 |