Potassium tert-butoxide → HCID 136368383, compound

Participants

Reaction Steps

In analogy to the procedure described in example 78.4, 2,5-dichloro-N-{1-imino-2-[2-(3-trifluoromethoxy-phenyl)-ethoxy]-ethyl}-nicotinamide was treated with KOtBu to obtain 6-chloro-2-[2-(3-trifluoromethoxy-phenyl)-ethoxymethyl]-3H-pyrido[2,3-d]pyrimidin-4-one as colorless crystals. MS: m/e=400.1 [M+H+].

Provenance & Evidence