HCID 68567079, compound → HCID 135899195, compound

Participants

Reaction Steps

2-(2-[1,2,4]Triazol-1-yl-acetylamino)-nicotinamide (206 mg, 0.8 mmol) was dissolved in pyridine (4 ml). The solution was microwaved for 15 min at 150° C. The solvent was removed in vacuo, and the residue purified by chromatography on silica (dichloromethane/methanol gradient) to yield 2-[1,2,4]triazol-1-ylmethyl-3H-pyrido[2,3-d]pyrimidin-4-one (18 mg, 72 μmol; 9%) as a yellow solid. MS (m/e): 229.1 [M+H+].

Provenance & Evidence