HuagongsheHuagongshe Chemistry Print Report · For research reference only
60222-56-2 → HCID 135899217, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 60222-56-2 | HCID 12293187 | — |
| Reactant | Potassium tert-butoxide | HCID 23665647 | — |
| Reactant | HCID 136345786 | HCID 136345786 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 135899217 | HCID 135899217 | — |
Reaction Steps
In analogy to the procedure described in example 97.3, 2-chloro-5-methyl-3H-pyrido[2,3-d]pyrimidin-4-one hydrochloride was reacted with 3-(2-chloro-phenoxy)-propan-1-ol [60222-56-2] in DMSO in the presence of molecular sieves and potassium tert-butylate to give the title compound as off-white crystals. MS: m/e=346.1 [M+H+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07572801B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-0c3d6ae62c7b44b293c03ae728512d0f |
| Source note | uspto-grants-2009_08 |