HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,5-difluoropyridine-3-carboxylic Acid → 6-Fluoro-2-[2-(3-fluoro-phenyl)-ethoxymethyl]-3H-pyrido[2,3-d]pyrimidin-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,5-difluoropyridine-3-carboxylic Acid | HCID 11815999 | — |
| Reactant | 2-[2-(3-Fluoro-phenyl)-ethoxy]-acetamidine hydrochloride | HCID 68568001 | — |
| Product | 6-Fluoro-2-[2-(3-fluoro-phenyl)-ethoxymethyl]-3H-pyrido[2,3-d]pyrimidin-4-one | HCID 136368388 | — |
Reaction Steps
The title compound was prepared in analogy to example 85 from 2,5-difluoropyridine-3-carboxylic acid and 2-[2-(3-fluoro-phenyl)-ethoxy]-acetamidine hydrochloride (example 101). Light brown solid. MS: m/e=318.2 [M+H+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07572801B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-47d341a147ab4460966df5f53f724da9 |
| Source note | uspto-grants-2009_08 |